Research Project
Full description This work reports the results of an RNA-sequencing study on the skeletal muscle samples of motor neurone disease cases and healthy controls, utilizing the counts of genes as quantified by the command-line STAR/Featurecounts and Salmon tools, with DESeq2 used to merge technical replicates and normalize the counts. Additionally, we conducted a differential transcript analysis on isoform-level counts as generated by Salmon, as well as a supplementary analysis on an overlapping set of blood samples.