Research Grant
[Cite as https://purl.org/au-research/grants/arc/DP0208082]Researchers: Dr Daniel Markovich (Chief Investigator)
Brief description The sulfate anion transporter gene, Sat1: physiology, regulation and developmental expression. Sulfate is an essential nutrient for cell growth and survival. The kidneys and liver help regulate sulfate levels in the body, by yet unknown mechanisms. Recently, we cloned a gene, Sat1, expressed in mouse liver and kidneys, which may be responsible for body sulfate maintenance. In this study, we will determine the physiological importance of Sat1 in cell growth/survival and in controlling body sulfate levels. We will generate and characterise a Sat1 lacking mouse, study its expression during development and its effects on other genes. We will elucidate how body sulfate levels are maintained and its importance in cell growth/development.
Funding Amount $141,000
Funding Scheme Discovery Projects
- PURL : https://purl.org/au-research/grants/arc/DP0208082
- ARC : DP0208082