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Confocal images showing the localization of RhoA and p190B RhoGAP at the apical adherens junctions in MCF-7 cells transfected with non-targeting Ctrl siRNA (Ctrl) or ROCK-1 siRNA (ROCK-1KD) and 48 hours later treated with either blebbistatin (100μM, 2 hours) alone (BLB) or in combination with ROCK-1 KD (ROCK-1 KD+BLB). Cells were fixed with methanol and stained for p190B Rho GAP or fixed with TCA and stained for RhoA.Issued: 2016
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Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions
local : UQ:370500
Priya, Rashmi, Gomez, Guillermo A., Budnar, Srikanth, Verma, Suzie, Cox, Hayley L., Hamilton, Nicholas A. and Yap, Alpha S. (2015). Feedback regulation through myosin II confers robustness on RhoA signalling at E-cadherin junctions. Nature Cell Biology, 17 (10), 1282-1293. doi: 10.1038/ncb3239
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local : UQ:289097
Institute for Molecular Bioscience - Publications
local : UQ:3858
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- DOI : 10.14264/UQL.2017.312