Structural studies of plant disease resistance proteins [ 2002-01-01 - 2004-12-31 ]

Research Grant

Researchers: Bostjan Kobe (Chief Investigator) ,  Dr Peter Anderson (Chief Investigator) ,  Professor Bostjan Kobe (Chief Investigator) ,  Professor Bostjan Kobe (Chief Investigator) ,  Dr Jeffrey Ellis (Partner Investigator)

Brief description Structural studies of plant disease resistance proteins. Plant cells have evolved a gene-for-gene disease resistance mechanism, involving an interaction of a plant-derived receptor with a specific pathogen-derived molecule. Currently, plant breeders are restricted to the resistance genes available in particular crop species or sexually compatible relatives. In the last few years, several plant disease resistance genes have been identified, providing a foundation for studying the molecular basis of the resistance process. We propose to obtain three-dimensional structural information on representative R proteins and their ligand complexes. This will form the basis for modifying existing resistance genes to confer resistance to new diseases, resulting in large economic benefits.

Funding Amount $318,000

Funding Scheme Discovery Projects

View this grant in the ARC Data Portal