Data

Sex-specific GWAS summary statistics for angina from "Investigating the potential causal relationship between parity and long-term maternal cardiometabolic health outcomes using Mendelian randomization"

The University of Queensland
Dr Gunn-Helen Moen (Aggregated by) Dr Gunn-Helen Moen (Aggregated by) Professor David Evans (Aggregated by) Professor David Evans (Aggregated by)
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.48610/6bf12ce&rft.title=Sex-specific GWAS summary statistics for angina from Investigating the potential causal relationship between parity and long-term maternal cardiometabolic health outcomes using Mendelian randomization&rft.identifier=RDM ID: a7b2ae66-624e-4090-8e6d-9baf5bfbdb77&rft.publisher=The University of Queensland&rft.description=Sex-stratified genome-wide association study (GWAS) of angina, performed in UK Biobank participants of European ancestry. Case/control definitions are provided in Supplementary Table 3. Individuals who withdrew consent or failed standard quality checks (e.g., sex mismatch, high heterozygosity, missingness, sex chromosome aneuploidy) were excluded. GWAS were performed using REGENIE. Models were adjusted for the first five genetic principal components, birth year, and genotyping batch. Female GWAS included 10,602 cases and 157,695 controls; male GWAS included 18,572 cases and 114,964 controls. Positions are given in genome build 38 (b38). Output columns are: CHROM (chromosome), GENPOS (base-pair position, b38), SNP (variant ID; rsID where available), ALLELE0 (non-effect allele), ALLELE1 (effect allele), A1FREQ (effect allele frequency), INFO (imputation information score), N (sample size), BETA (effect size per copy of ALLELE1, log-odds scale), SE (standard error), and P (p-value). For further details on the analytical pipeline and quality control procedures, see Supplementary Material 2.0 and Supplementary Figure 4.&rft.creator=Dr Gunn-Helen Moen&rft.creator=Dr Gunn-Helen Moen&rft.creator=Professor David Evans&rft.creator=Professor David Evans&rft.date=2026&rft_rights= https://guides.library.uq.edu.au/deposit-your-data/license-reuse-data-agreement&rft_subject=eng&rft_subject=Genome-wide association study&rft_subject=Genotyping&rft_subject=Biobank&rft_subject=Genetic association&rft_subject=Angina&rft_subject=Mendelian inheritance&rft_subject=Cohort&rft_subject=SNP&rft_subject=Statistical and quantitative genetics&rft_subject=Bioinformatics and computational biology&rft_subject=BIOLOGICAL SCIENCES&rft_subject=Genomics&rft_subject=Genetics&rft_subject=Cardiology (incl. cardiovascular diseases)&rft_subject=Cardiovascular medicine and haematology&rft_subject=BIOMEDICAL AND CLINICAL SCIENCES&rft.type=dataset&rft.language=English Access the data
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[email protected]
Institute for Molecular Bioscience

Full description

Sex-stratified genome-wide association study (GWAS) of angina, performed in UK Biobank participants of European ancestry. Case/control definitions are provided in Supplementary Table 3. Individuals who withdrew consent or failed standard quality checks (e.g., sex mismatch, high heterozygosity, missingness, sex chromosome aneuploidy) were excluded. GWAS were performed using REGENIE. Models were adjusted for the first five genetic principal components, birth year, and genotyping batch. Female GWAS included 10,602 cases and 157,695 controls; male GWAS included 18,572 cases and 114,964 controls. Positions are given in genome build 38 (b38). Output columns are: CHROM (chromosome), GENPOS (base-pair position, b38), SNP (variant ID; rsID where available), ALLELE0 (non-effect allele), ALLELE1 (effect allele), A1FREQ (effect allele frequency), INFO (imputation information score), N (sample size), BETA (effect size per copy of ALLELE1, log-odds scale), SE (standard error), and P (p-value). For further details on the analytical pipeline and quality control procedures, see Supplementary Material 2.0 and Supplementary Figure 4.

Issued: 2026

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Subjects
Angina | Biological Sciences | Biomedical and Clinical Sciences | Biobank | Bioinformatics and Computational Biology | Cardiology (Incl. Cardiovascular Diseases) | Cardiovascular Medicine and Haematology | Cohort | Genetic association | Genetics | Genome-wide association study | Genomics | Genotyping | Mendelian inheritance | SNP | Statistical and Quantitative Genetics | eng |

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Identifiers
ACN 633 798 857