Full description
This data represents the free fatty acid (FFA) and phospholipid (PL) response to auditory fear conditioning (AFC) across the rat brain in the presence or absence of a memory blocking agent. Four experimental conditions were used, each applied to a cohort of 8 rat: saline injected (control) animals, unpaired AFC stimuli (SU); saline injected animals, paired stimuli (SP); CPP (NMDA antagonist) injected animals, unpaired AFC stimuli (CU); CPP injected animals, paired AFC stimuli (CP). Tissue was collected from 6 brain regions CeA – central amygdala, BLA – basolateral amygdala, PFC – prefrontal coretex, DH – dorsal hippocampus, VH – ventral hippocampus, CB – cerebellum Lipidomics analysis using targeted LCMSMS was performed for FFA – free fatty acid, PA – phosphatidic acid, PC- phosphatidylcholine, PE – phosphatidylcholine, PG – phosphatidylglycerol, PS – phosphatidylserine Data contains the quantified abundance for each targeted lipid species for each of the 4 AFC conditions, 8 animals, 6 brain regionsIssued: 04 05 2021
Subjects
AFC |
Medical and Health Sciences |
Neurosciences |
auditory fear conditioning |
eng |
free fatty acid |
rat brain |
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Other Information
Saturated free fatty acids and association with memory formation
local : UQ:60ffa36
Wallis, Tristan P., Venkatesh, Bharat G., Narayana, Vinod K., Kvaskoff, David, Ho, Alan, Sullivan, Robert K., Windels, François, Sah, Pankaj and Meunier, Frédéric A. (2021). Saturated free fatty acids and association with memory formation. Nature Communications, 12 (1) 3443, 3443. doi: 10.1038/s41467-021-23840-3
Research Data Collections
local : UQ:289097
Identifiers
- DOI : 10.14264/12793DC