Data

PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbendazole into Prostrate Cancer Cells

Queensland University of Technology
Koohi Moftakhari Esfahani, Maedeh ; Alavi, Seyedebrahim ; J. Cabot, Peter ; Islam, Nazrul ; L. Izake, Emad
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=http://researchdatafinder.qut.edu.au/individual/n12166&rft.title=PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbendazole into Prostrate Cancer Cells&rft.identifier=http://researchdatafinder.qut.edu.au/individual/n12166&rft.publisher=Queensland University of Technology&rft.description=Low water solubility and bioavailability limit the clinical application of drugs. Solubilizing agents, such as Mobil Composition of Matter Number 41 (MCM) as a drug carrier, can improve the water solubility of the drugs. In this study, PEGylated MCM nanoparticles were synthesised and loaded with fenbendazole, which is a potential anticancer drug, to improve its solubility and, as a result, its cytotoxicity effect against human prostate cancer PC-3 cells. All data related to this study are contained within the article, Esfahani, Maedeh Koohi Moftakhari, Alavi, Seyed Ebrahim, Cabot, Peter J., Islam, Nasrul, & Izake, Emad L. (2021) PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbenzadole into Prostrate Cancer Cells. Pharmaceutics, 13(10), Article number: 1605. . &rft.creator=Koohi Moftakhari Esfahani, Maedeh &rft.creator=Alavi, Seyedebrahim &rft.creator=J. Cabot, Peter &rft.creator=Islam, Nazrul &rft.creator=L. Izake, Emad &rft.date=2022&rft.edition=1&rft.relation=https://eprints.qut.edu.au/214034/&rft.coverage=153.317870,-26.996845 152.668523,-26.996845 152.668523,-27.767441 153.317870,-27.767441 153.317870,-26.996845&rft_rights=© Maedeh Koohi Moftakhari Esfahani, 2022. &rft_rights=Creative Commons Attribution 3.0 http://creativecommons.org/licenses/by/4.0/&rft_subject=Biomaterials&rft_subject=Biomedical engineering&rft_subject=ENGINEERING&rft_subject=Nanotechnology&rft_subject=Biotechnology&rft.type=dataset&rft.language=English Access the data

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CC-BY

Creative Commons Attribution 3.0
http://creativecommons.org/licenses/by/4.0/

© Maedeh Koohi Moftakhari Esfahani, 2022.

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Contact Information

Postal Address:
Mrs Maedeh Koohi Moftakhari Esfahani

maedeh.koohi@hdr.qut.edu.au

Full description

Low water solubility and bioavailability limit the clinical application of drugs. Solubilizing agents, such as Mobil Composition of Matter Number 41 (MCM) as a drug carrier, can improve the water solubility of the drugs. In this study, PEGylated MCM nanoparticles were synthesised and loaded with fenbendazole, which is a potential anticancer drug, to improve its solubility and, as a result, its cytotoxicity effect against human prostate cancer PC-3 cells.

All data related to this study are contained within the article, "Esfahani, Maedeh Koohi Moftakhari, Alavi, Seyed Ebrahim, Cabot, Peter J., Islam, Nasrul, & Izake, Emad L. (2021) PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbenzadole into Prostrate Cancer Cells. Pharmaceutics, 13(10), Article number: 1605. ".

Data time period: 07 2020 to 08 2021

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153.317870,-26.996845 152.668523,-26.996845 152.668523,-27.767441 153.317870,-27.767441 153.317870,-26.996845

152.9931965,-27.382143

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