Low water solubility and bioavailability limit the clinical application of drugs. Solubilizing agents, such as Mobil Composition of Matter Number 41 (MCM) as a drug carrier, can improve the water solubility of the drugs. In this study, PEGylated MCM nanoparticles were synthesised and loaded with fenbendazole, which is a potential anticancer drug, to improve its solubility and, as a result, its cytotoxicity effect against human prostate cancer PC-3 cells.
All data related to this study are contained within the article, "Esfahani, Maedeh Koohi Moftakhari, Alavi, Seyed Ebrahim, Cabot, Peter J., Islam, Nasrul, & Izake, Emad L. (2021) PEGylated Mesoporous Silica Nanoparticles (MCM-41): A Promising Carrier for the Targeted Delivery of Fenbenzadole into Prostrate Cancer Cells. Pharmaceutics, 13(10), Article number: 1605. ".
Data time period: 07 2020 to 08 2021
153.31787,-26.99685 152.66852,-26.99685 152.66852,-27.76744 153.31787,-27.76744 153.31787,-26.99685
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- Local : 10378.3/8085/1018.17437
- URI : http://researchdatafinder.qut.edu.au/individual/n12166