Multimodal ex-vivo MRI and tissue clearing dataset of porcine kidney

Full description

Six porcine kidney cortical samples (~15 - 40 mm3) were scanned at 16.4 T with 30 micron isotropic resolution using T2- and T2*-weighted imaging, quantitative relaxation mapping, diffusion-weighted imaging (DWI), and quantitative susceptibility mapping (QSM) sequences. Post-MRI, samples underwent tissue clearing, SYTOX Green fluorescent nuclear staining and Fast Green histochemical staining of collagen and confocal microscopy. Three-dimensional MR and optical images were co-registered using anatomical landmarks to enable precise localisation of individual glomeruli. The datasets are arranged in 4 folders: - raw MRI data - processed MRI data - processed Tissue Clearing microscopy data - segmentation masks for segmentation of spin-echo and gradient-echo MRI data