Data

High-Throughput Synthesis and Evaluation of Antiviral Copolymers to Target Enveloped Viruses

Queensland University of Technology
Mengist, Hylemarian ; Denman, Paul ; Frost, Charlotte ; Sng, Julian ; Logan, Saskia ; Barner, Leonie ; Spann, Kirsten ; Fairfull-Smith, Kathryn
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.25912/RDF_1721879623130&rft.title=High-Throughput Synthesis and Evaluation of Antiviral Copolymers to Target Enveloped Viruses&rft.identifier=10.25912/RDF_1721879623130&rft.publisher=Queensland University of Technology&rft.description=This dataset includes characterisation data for copolymers synthesised by high throughput PET-RAFT photopolymerisation strategy, including NMR and SEC analysis of polymers, and raw results from immunoplaque and cytotoxicity assays used to evaluate antiviral activity. Polymer association with models of viral membranes by Langmuir lipid monolayers are also included. Python scripts used for analysis of data set are included as a Jupyter Notebook. New antiviral polymers to deactivate eneveloped viruses were synthesised and evaluated by a high-throughput experimental workflow. &rft.creator=Mengist, Hylemarian &rft.creator=Denman, Paul &rft.creator=Frost, Charlotte &rft.creator=Sng, Julian &rft.creator=Logan, Saskia &rft.creator=Barner, Leonie &rft.creator=Spann, Kirsten &rft.creator=Fairfull-Smith, Kathryn &rft.date=2024&rft.edition=1&rft.coverage=153.044839,-27.467359&rft_rights=© Queensland University of Technology, 2024.&rft_rights=Creative Commons Attribution-Share Alike 3.0 http://creativecommons.org/licenses/by-sa/4.0/&rft_subject=High-throughput polymerisation&rft_subject=Lipid monolayers&rft_subject=Antivirals&rft_subject=Macromolecular and materials chemistry &rft.type=dataset&rft.language=English Access the data

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Open Licence view details
CC-BY-SA

Creative Commons Attribution-Share Alike 3.0
http://creativecommons.org/licenses/by-sa/4.0/

© Queensland University of Technology, 2024.

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Contact Information

Postal Address:
Dr Nathan Boase
Ph: +61731382429

nathan.boase@qut.edu.au

Full description

This dataset includes characterisation data for copolymers synthesised by high throughput PET-RAFT photopolymerisation strategy, including NMR and SEC analysis of polymers, and raw results from immunoplaque and cytotoxicity assays used to evaluate antiviral activity. Polymer association with models of viral membranes by Langmuir lipid monolayers are also included. Python scripts used for analysis of data set are included as a Jupyter Notebook.

New antiviral polymers to deactivate eneveloped viruses were synthesised and evaluated by a high-throughput experimental workflow.

Data time period: 2022 to 2024

This dataset is part of a larger collection

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153.04484,-27.46736

153.044839,-27.467359

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