Functional analysis of the Rab GAP AS160 [ 2014 - 2016 ]

Research Grant

Researchers: Dr Jacqueline Stoeckli (Principal investigator) ,  Prof David James

Brief description Insulin triggers glucose uptake into fat and muscle tissue, a process that is defective in type 2 diabetes. Insulin does this by triggering a complex cascade of actions once it binds to muscle and fat cells. We will analyse the function of a crucial protein within this cascade. This protein is mutated in humans with severe insulin resistance and our proposed project will dissect how this protein works potentially providing a novel drug target to treat diabetes.

Funding Amount $AUD 485,138.41

Funding Scheme Project Grants

Notes Standard Project Grant