Exploitation of a Novel Drug Target for Controlling Animal Trypanosomiasis. [ 2002-07-21 - 2004-12-31 ]

Research Grant

Researchers: A/Prof James Reynoldson (Chief Investigator) ,  Dr Anthony Armson (Chief Investigator) ,  Prof Richard Thompson (Chief Investigator) ,  Professor Simon Reid (Chief Investigator) ,  Professor Simon Reid (Chief Investigator)
View all 6 related researchers

Brief description Exploitation of a Novel Drug Target for Controlling Animal Trypanosomiasis. Trypanosomiasis greatly reduces livestock productivity in countries where it is endemic and is a threat to livestock and native wildlife in countries such as Australia where it is exotic but there is a risk of entry. New trypanocidal drugs with different modes of action are urgently needed to overcome growing resistance. This project aims to characterise trypanosome tubulin and, with this information, produce new tubulin-binding compounds for assessment in vitro and in vivo. Upon completion of the project it is expected that drug binding sites on trypanosome tubulin will be characterised and at least one candidate for clinical trials identified.

Funding Amount $379,493

Funding Scheme Linkage Projects

View this grant in the ARC Data Portal