Data

Does varying the ingestion duration of sodium citrate influence blood alkalosis and gastrointestinal symptoms?

Deakin University
Dr Amelia Carr (Associated with) Mr Charles Urwin (Aggregated by)
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.26187/tkah-h625&rft.title=Does varying the ingestion duration of sodium citrate influence blood alkalosis and gastrointestinal symptoms?&rft.identifier=10.26187/tkah-h625&rft.publisher=Deakin University&rft.description=Objectives: To compare blood alkalosis, gastrointestinal symptoms and indicators of strong ion difference after ingestion of 500 mg.kg-1 BM sodium citrate over four different durations. Methods: Sixteen healthy and active participants ingested 500 mg.kg-1 BM sodium citrate in gelatine capsules over a 15, 30, 45 or 60 min period using a randomized cross-over experimental design. Gastrointestinal symptoms questionnaires and venous blood samples were collected before ingestion, immediately post-ingestion, and every 30 min for 480 min post-ingestion. Blood samples were analysed for blood pH, [HCO3-], [Na+], [Cl-] and plasma [citrate]. Linear mixed models were used to estimate the effect of the ingestion protocols. Results: For all treatments, blood [HCO3-] was significantly above baseline for the entire 480 min post-ingestion period, and peak occurred 180 min post-ingestion. Blood [HCO3-] and blood pH were significantly above baseline and not significantly below the peak between 150-270 min post-ingestion. Furthermore, blood pH and [HCO3-] were significantly lower for the 60 min ingestion duration when compared to the other treatments. Gastrointestinal symptoms were minor for all treatments; the mean total session symptoms ratings (all times summed together) were between 9.8 and 11.6 from a maximum possible rating of 720. Conclusion: Based on the findings of this investigation, sodium citrate should be ingested over a duration of less than 60 min (15, 30 or 45 min), and completed 150-270 min before exercise. &rft.creator=Mr Charles Urwin&rft.date=2021&rft_rights=2021, Deakin University&rft_rights=Open Access&rft_subject=Ergogenic aids&rft_subject=Buffering agents&rft_subject=Dietary supplementation&rft_subject=Human Movement and Sports Science not elsewhere classified&rft_subject=MEDICAL AND HEALTH SCIENCES&rft_subject=HUMAN MOVEMENT AND SPORTS SCIENCE&rft_subject=Expanding Knowledge in the Medical and Health Sciences&rft_subject=EXPANDING KNOWLEDGE&rft_subject=EXPANDING KNOWLEDGE&rft_subject=Pure&rft.type=dataset&rft.language=English Access the data

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2021, Deakin University

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Creative Commons Attribution 4.0 International

Contact Information

Postal Address:
Urwin, Charles

c.urwin@deakin.edu.au

Full description

Objectives: To compare blood alkalosis, gastrointestinal symptoms and indicators of strong ion difference after ingestion of 500 mg.kg-1 BM sodium citrate over four different durations. Methods: Sixteen healthy and active participants ingested 500 mg.kg-1 BM sodium citrate in gelatine capsules over a 15, 30, 45 or 60 min period using a randomized cross-over experimental design. Gastrointestinal symptoms questionnaires and venous blood samples were collected before ingestion, immediately post-ingestion, and every 30 min for 480 min post-ingestion. Blood samples were analysed for blood pH, [HCO3-], [Na+], [Cl-] and plasma [citrate]. Linear mixed models were used to estimate the effect of the ingestion protocols. Results: For all treatments, blood [HCO3-] was significantly above baseline for the entire 480 min post-ingestion period, and peak occurred 180 min post-ingestion. Blood [HCO3-] and blood pH were significantly above baseline and not significantly below the peak between 150-270 min post-ingestion. Furthermore, blood pH and [HCO3-] were significantly lower for the 60 min ingestion duration when compared to the other treatments. Gastrointestinal symptoms were minor for all treatments; the mean total session symptoms ratings (all times summed together) were between 9.8 and 11.6 from a maximum possible rating of 720. Conclusion: Based on the findings of this investigation, sodium citrate should be ingested over a duration of less than 60 min (15, 30 or 45 min), and completed 150-270 min before exercise.

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IDENTIFIER: 10.26187/tkah-h625

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