Research Grant
[Cite as https://purl.org/au-research/grants/arc/DP260105164]Researchers: O'Brien, Terence (Chief Investigator) , Sandy Shultz (Chief Investigator) , Stuart McDonald (Chief Investigator) , William O'Brien (Chief Investigator) , Mazdak Ghajari (Partner Investigator)
Brief description Combining biomechanics and biomarkers to establish brain injury thresholds. This project aims to define biomechanical thresholds for brain injury, overcoming limitations of prior efforts reliant on peak acceleration metrics and controlled lab tests that fail to capture the complexity of brain tissue mechanics. By integrating head kinematic data from instrumented mouthguards, MRI-based finite element modelling of brain strain, and brain injury-specific blood biomarkers, this project seeks to link mechanical strain with biological responses. Expected outcomes include identifying strain thresholds derived from wearable sensor data, facilitating timely detection of high-risk impacts. This approach promises significant benefits, enhancing injury detection and informing helmet design for sports, military, and transport.
Funding Amount $799,866
Funding Scheme Discovery Projects
- PURL : https://purl.org/au-research/grants/arc/DP260105164
- ARC : DP260105164