Research Grant
[Cite as https://purl.org/au-research/grants/arc/DP230100721]
Researchers:
Guijt, Rosanna
(Chief Investigator)
,
Louis Jun Ye Ong
(Chief Investigator)
,
Professor Kirsten Spann
(Chief Investigator)
,
Rosanne Guijt
(Chief Investigator)
,
Yi-Chin Toh
(Chief Investigator)
View all 8 related researchers
Brief description A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.
Funding Amount $501,180
Funding Scheme Discovery Projects
- PURL : https://purl.org/au-research/grants/arc/DP230100721
- ARC : DP230100721