Research Grant
[Cite as https://purl.org/au-research/grants/arc/DP230100415]Researchers: Lara Malins (Chief Investigator) , ARC Linkage Grant LP1701000985 (Funded by) , The Australian National University (Managed by)
Brief description Advances in Peptide Synthesis: Exploiting Underutilised Functional Groups. The translation of therapeutically-relevant classes of peptides to the clinic is often limited by chemists' ability to synthesise these complex biomolecules efficiently and sustainably. This project aims to develop new tools for the preparation of designer peptides that are broadly inspired by an underutilised reactive group found in naturally-occurring peptide sequences. Expected outcomes encompass health and economic benefits for the Australian community, including: the first approach to a class of promising antibiotic peptide natural product analogues, the development of a mild electrochemical approach to peptide modification, and the production of a library of novel amino acids for incorporation into potential antibiotic leads.
Funding Amount $424,590
Funding Scheme Discovery Projects
- PURL : https://purl.org/au-research/grants/arc/DP230100415
- ARC : DP230100415