grant

Discovery Projects - Grant ID: DP210103595 [ 2021-11-09 - 2024-11-08 ]

Research Grant

[Cite as https://purl.org/au-research/grants/arc/DP210103595]

Researchers: Dr Lizhong He (Chief Investigator) ,  Travis Beddoe (Chief Investigator) ,  Victoria Haritos (Chief Investigator) ,  Philipp Kukura (Partner Investigator) ,  Yan Sun (Partner Investigator)

Brief description Engineer enzyme nanoparticles as antibiotic alternatives for agriculture. Antibiotic usage in agriculture contributes to spread of resistant bacteria. Existing antibiotic alternatives to minimize such usage are focused on growth promotion of animals and infection prevention, but lack efficient treatment. This project aims to engineer enzyme nanoparticles, with synergy from multiple enzymes, to confer better antibacterial abilities against livestock pathogens. It will combine protein engineering, nanotechnology and biophysics to develop new enzyme nanoparticles that can be manufactured at low-cost through self-assembly process. The intended outcome is knowledge on molecular engineering of enzyme nanoparticles and innovative agriculture biotechnology for treatment of bacterial infectious diseases in livestock.

Funding Amount $293,564

Funding Scheme Discovery Projects

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Identifiers
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ACN 633 798 857