Research Grant
[Cite as https://purl.org/au-research/grants/arc/DP140103164]Researchers: Dr Lachlan Coin (Chief Investigator) , Dr Lachlan Coin (Chief Investigator) , Dr Mathieu Lajoie (Chief Investigator) , Dr Clive Hoggart (Partner Investigator) , Prof Nicholas Martin (Partner Investigator)
Brief description Using population resequencing data to investigate the evolutionary role and functional impact of inversion polymorphisms. The project will use population re-sequencing data to generate high resolution haplotype maps of inversion polymorphisms in multiple human populations comprising more than 5,000 individuals. These maps will be used to impute inversion polymorphsisms in genotyped samples of more than 100,000 individuals, facilitated by development of novel algorithms for mapping inversion polymorphism from population sequence data. Finally, the project will use this map to assess the functional impact and evolutionary role of inversions, by assessing their effect on quantitative traits and assessing measures of selection and population differentiation.
Funding Amount $90,000
Funding Scheme Discovery Projects
- PURL : https://purl.org/au-research/grants/arc/DP140103164
- ARC : DP140103164