Research Grant
[Cite as https://purl.org/au-research/grants/arc/LP0219363]Researchers: Dr Jennifer Wilson (Chief Investigator) , Dr Robin Thomson (Chief Investigator) , Prof Mark von Itzstein (Chief Investigator) , Dr Tracey Brown (Partner Investigator)
Brief description Development of Multivalent Hyaluronan Derivative Therapeutics. Over-expression of the hyaluronan receptor CD44 has been identified at pathological sites of diseases such as cancer, psoriasis, arthritis and asthma. The research described in this proposal aims to develop novel therapeutic compounds which target CD44 whilst eliciting a therapeutic index. The design of these new therapeutics is based on a template structure which incorporates known cytotoxic or anti-fungal agentsas well as hyaluronan, a naturally occurring carbohydrate, ubiquitous in nature.
Funding Amount $67,635
Funding Scheme Linkage Projects
- PURL : https://purl.org/au-research/grants/arc/LP0219363
- ARC : LP0219363