Computational Modeling of RNA Control Networks [ 2003-01-01 - 2007-12-31 ]

Research Grant

Researchers: Dr Jennifer Hallinan (Chief Investigator) ,  John Mattick (Chief Investigator) ,  Professor Janet Wiles (Chief Investigator) ,  ARC Linkage Grant LP1701000985 (Funded by)

Brief description Computational Modeling of RNA Control Networks. One of the most exciting new ideas for understanding the regulation of gene expression involves the contribution of intronic and other non-protein coding RNAs to regulatory networks within cells. This novel role for intronic RNA is currently making headlines within the molecular biology community but has not yet been modelled computationally. The network of genetic regulatory interactions forms a complex system which is amenable to computational analysis. This project aims to extend current models to incorporate intronic RNA feedback control, complementing parallel studies in vivo, and computationally testing ideas essential to the theoretical understanding of the basis of life.

Funding Amount $195,000

Funding Scheme Discovery Projects

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