Full description
The project studied the molecular mechanisms of botulinum neurotoxin type A (BoNT/A) binding and endocytosis in cultured primary hippocampal neurons. The collection includes all the original single molecule imaging data (single and dual channel), electron microscopy and electron tomography data, fluorescent imaging data, as well as electrophysiological recordings, presented in Figures 1-5 in Joensuu et al., 2023 EMBO J (article doi: 10.15252/embjoj.2022112095). The corresponding figure folders also contain all the original quantification files.Issued: 2023
User Contributed Tags
Login to tag this record with meaningful keywords to make it easier to discover
Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG‐Syt1 ‐ SV2 plasma membrane nanocluster for synaptic vesicle entry
local : UQ:1918c33
Joensuu, Merja, Syed, Parnayan, Saber, Saber H., Lanoue, Vanessa, Wallis, Tristan P., Rae, James, Blum, Ailisa, Gormal, Rachel S., Small, Christopher, Sanders, Shanley, Jiang, Anmin, Mahrhold, Stefan, Krez, Nadja, Cousin, Michael A., Cooper‐White, Ruby, Cooper‐White, Justin J., Collins, Brett M., Parton, Robert G., Balistreri, Giuseppe, Rummel, Andreas and Meunier, Frédéric A. (2023). Presynaptic targeting of botulinum neurotoxin type A requires a tripartite PSG‐Syt1 ‐ SV2 plasma membrane nanocluster for synaptic vesicle entry. The EMBO Journal, 42 (13) e112095, e112095. doi: 10.15252/embj.2022112095
Research Data Collections
local : UQ:289097
- Local : RDM ID: 3d68b6a0-f3bb-11ed-93ec-2b6f3205d72a
- DOI : 10.48610/06039FF