grant

Biochemical, Genomic and Phenomic Analysis of Gastric Parietal Cells from Wildtype and Mutant Mice [ 2003-01-01 - 2007-12-31 ]

Research Grant

[Cite as https://purl.org/au-research/grants/arc/DP0343446]

Researchers: A/Prof Ian van Driel (Chief Investigator) ,  A/Prof Paul Gleeson (Chief Investigator) ,  Dr Seong Tan (Partner Investigator)

Brief description Biochemical, Genomic and Phenomic Analysis of Gastric Parietal Cells from Wildtype and Mutant Mice. The interface between the cell and its environment is the cell membrane. Signals, nutrients, and ions all have to cross this barrier. In addition, the cells contain many specialized intracellular membranous compartments. We know little about the signals that direct the synthesis of these structures and determine their final composition and shape. This grant will utilize acid secretory cells in the stomach to examine these questions because they contain a very extensive membrane system. We will use a state-of-the-art genetic and cell biological technologies to manipulate and analyse these cells in a whole animal setting.

Funding Amount $155,000

Funding Scheme Discovery Projects

View this grant in the ARC Data Portal

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Identifiers
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ACN 633 798 857