Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction

Full description

The dataset contains the surface characterisation of 3D-printed non-porous and micro-porous medical-grade polycaprolactone (mPCL) scaffolds via Fourier transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and microcomputed tomography. In addition, the mechanical properties of these scaffolds were tested by applying uniaxial compression using an Instron model 5848. 

Human serum albumin (HSA) and tannic acid (TA) were immobilised onto the surface of micro-porous mPCL scaffolds. Herein, we include the surface characterisation of the modified surfaces using FTIR, XPS, and fluorescein 5(6)-isothiocyanate (FITC)-labelling. Finally, the antibacterial in vitro efficacy of HSA/TA-coated scaffolds was assessed in a 2D zone of inhibition assay against S. aureus and P. aeruginosa. Nevertheless, since 2D zone of inhibition assays do not fully represent the interactions of coated scaffolds with bacteria in a realistic in vivo environment, a 3D in vitro assay was designed in order to investigate the antibacterial properties of coated scaffolds against S. aureus in suspension.

The data is available under the 'Access the data' link, as well as in the Supplementary Material section of the article 'Antibacterial Albumin-Tannic Acid Coatings for Scaffold-Guided Breast Reconstruction'.