Zinc as an antimicrobial agent and its effect on the pathogenesis of Group A Streptococcus [ 2015 - ]

Research Grant

Researchers: Prof Alastair McEwan (Principal investigator)

Brief description This proposal focuses on Group A Streptococcus (GAS), a human pathogen estimated to cause 600,000 human deaths per year. We have shown that the host immune system uses zinc as an antibacterial agent and that GAS has processes that protect against zinc overload. We will determine the way in which zinc mobilization controls GAS infection and how GAS responds to to an increase in zinc concentration. The results will provide new insights into zinc’s role in protection against bacterial infections.

Funding Amount $341,398.00

Funding Scheme Project Grants

Notes Standard Project Grant