grant

Wnt-5a signalling - a novel therapy for triple negative and Tamoxifen resistant breast cancer patients [ 2010 - 2012 ]

Also known as: New treatments for triple negative breast cancer patients

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/630458]

Researchers: Dr Caroline Ford (Principal investigator)

Brief description Breast cancer is the most common cancer in women. Commonly used drugs target the estrogen receptor (ER). However, one third of breast cancer patients lack ER, and do not respond to treatment. Cancers that lack ER also lack a gene called Wnt5a, which is linked to better prognosis. We have shown that fixing Wnt5a can restore ER allowing cells to respond to Tamoxifen. We would now test this in animals, in the hope of developing a new drug for breast cancer patients currently with limited options.

Funding Amount $AUD 330,534.81

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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Identifiers
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ACN 633 798 857