West Nile virus replication and host response [ 2008 - 2011 ]

Research Grant

Researchers: Prof Alexander Khromykh (Principal investigator) ,  Dr Wenjun Liu ,  Prof Roy Hall ,  Prof Shizuo Akira

Brief description We seek to gain a detailed understanding of how interactions between the West Nile virus proteins and host factors involved in the IFN response determine the outcome of virus infection. Better understanding of the mechanisms employed by this highly pathogenic virus to disable the mammalian host's IFN response will have wider implications for our understanding of other human diseases such as cancer, autoimmunity and provide new avenues for design of efficient antiviral and anticancer therapies.

Funding Amount $AUD 560,434.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant