How do the Vitamin D Receptor activation genes CYP27B1 and CYP24A1 alter susceptibility to autoimmune diseases? [ 2013 - 2016 ]

Research Grant

Researchers: Prof David Booth (Principal investigator) ,  Dr Marcel Batten ,  Prof Christopher Liddle ,  Prof Graeme Stewart

Brief description Because Vitamin D deficiency has long been associated with autoimmune diseases, clinical trials with various forms of Vitamin D have been conducted and are underway. Yet the basis for the Vitamin D association has not been established. In 2012, two vitamin D genes were shown to alter susceptibility to autoimmune diseases. The goal of this project is to determine how these genes influence immune tolerance mechanisms, and so develop novel and improved therapeutic approaches based on Vitamin D.

Funding Amount $AUD 508,518.20

Funding Scheme Project Grants

Notes Standard Project Grant