Viral infection and TGFbeta impair glucocorticoid activity in epithelial cells [ 2014 - 2016 ]

Research Grant

Researchers: Prof Alastair Stewart (Principal investigator) ,  Dr Guillermo Lopez Campos ,  Dr Sarah Londrigan ,  Prof Jo Douglass ,  Prof Saman Halgamuge

Brief description Chronic inflammatory lung diseases like asthma and smokers lung are treated with combinations of anti-inflammatory drugs. Powerful anti-inflammatory types of steroid drugs are used in more severe disease. Even these powerful drugs are sometimes not effective enough. Our work is developing an understanding of how inflammation limits the anti-inflammatory effects of steroids and we are devising ways to overcome this with new drugs. We aim to improve treatment of chronic inflammatory diseases, especially those affecting the lung.

Funding Amount $AUD 617,699.64

Funding Scheme Project Grants

Notes Standard Project Grant