Vanin-3 signalling in osteoarthritis [ 2014 - ]

Research Grant

Researchers: Prof Amanda Fosang (Principal investigator) ,  Prof Philip Sutton

Brief description Osteoarthritis (OA) affects approximately 20% of Australians and costs billions each year in joint replacements. Therapies that halt joint destruction in OA are urgently needed. We hypothesise that the little-known gene, vanin -3, is a key regulator of OA disease pathways. Our project will map vanin-3 in the joint and reveal how much vanin-3 contributes to joint destruction in mice. We expect to find a link between vanin-3 and metabolic disorders and identify new targets for therapy.

Funding Amount $630,414.00

Funding Scheme Project Grants

Notes Standard Project Grant