Upregulating kallistatin to limit abdominal aortic aneurysm. [ 2015 - ]

Research Grant

Researchers: Prof Jonathan Golledge (Principal investigator) ,  Prof Philip Walker

Brief description Artery weakening or aneurysm is an important cause of mortality in older adults. Currently there are only surgical therapies for artery weakening. Novel drug therapies are needed for artery weakening. In this project the role of a protein which may inhibit artery weakening is investigated. We also investigate the role of a drug to modulate this protein. The project will include studies in pre-clinical models and a pilot clinical trial in patients.

Funding Amount $648,022.00

Funding Scheme Project Grants

Notes Standard Project Grant