The unstable, rupture-prone atherosclerotic plaque: Innovative methods for its detection and stabilisation [ 2017 - ]

Research Grant

Researchers: Prof Karlheinz Peter (Principal investigator) ,  Dr YungChih Chen

Brief description Heart attacks and strokes are most often caused by rupture of unstable atherosclerotic plaques resulting in clotting and vessel occlusion and ultimately irreversible damage of the heart or brain. We have generated a mouse model that reproduces these plaques as seen in humans. Based on this model and human unstable plaques 1) we have discovered/developed imaging technologies that can identify these dangerous plaques and 2) we will develop drugs that prevent plaque rupture.

Funding Amount $748,447.00

Funding Scheme Project Grants

Notes Standard Project Grant