Unraveling IL-1F7: A Neglected IL-1 Family Member with Big-Stage Potential [ 2011 - 2013 ]

Research Grant

Researchers: A/Pr Marcel Nold (Principal investigator) ,  Associate Professor Marcel Nold (Principal investigator) ,  Associate Professor Marcel Nold (Principal investigator) ,  Dr Claudia Nold

Brief description Cytokines are messenger proteins used by most cells of the body. Since their role as master regulators of many biological processes was discovered, cytokines have enjoyed the limelight of biomedical research. Anti-inflammatory cytokines are particularly coveted as they could replace side effect-prone anti-inflammatory drugs like aspirin. We identified an anti-inflammatory cytokine (IL-1F7) and revealed its protective activity in common, severe diseases like myocardial infarction. We will now explore how IL-1F7 exerts is protective properties.

Funding Amount $AUD 349,590.19

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant