grant

Unlocking the secrets of Royal Jelly: from recent breakthroughs to novel drugs targeting Anaplastic Lymphoma Kinase [ 2013 - 2015 ]

Also known as: Unlocking the secrets of Royal Jelly for novel drug discovery

Funded by National Health and Medical Research Council
Managed by Australian National University
Managed by The Australian National University
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1050593]

Researchers: Prof Ryszard Maleszka (Principal investigator) ,  The Australian National University (Managed by)

Brief description Nature is a source of incommensurable chemical diversity that throughout history have provided many useful bioactive compounds including anti-cancer drugs. Our recent results suggest that honeybees use royal jelly to regulate the expression of genes implicated in certain types of human cancer.The aim of this study is to identify inhibitors of cancer related genes in royal jelly and to understand the mechanism of their action. Our results could lead to novel combination therapies.

Funding Amount $AUD 348,763.91

Funding Scheme Project Grants

Notes Standard Project Grant

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Subjects
Biological Sciences | DNA methylation | Epigenetics (Incl. Genome Methylation and Epigenomics) | Genetics | cancer control | drug development | epigenetics | gene expression | receptor signalling | signalling pathways |
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