Understanding tissue responses to fluid resuscitation and blood transfusion during ovine sepsis to improve outcomes [ 2014 - 2018 ]

Research Grant

Researchers: Prof John Fraser (Principal investigator) ,  A/Pr Kiran Shekar ,  A/Pr Yoke Lin Fung ,  Prof Michael Reade

Brief description Annually, sepsis affects up to 30 million patients, killing more patients than the combined totals of breast, prostate and lung cancer. Fluid resuscitation is a cornerstone of sepsis therapy, aimed at improving oxygen delivery to key organs. Data now indicates that blood and non-blood fluids may worsen mortality. This study will investigate the mechanism of sepsis and the effect of blood and non-blood fluids, to provide data to clinicians which may reduce the vast global burden of this disease.

Funding Amount $AUD 980,810.56

Funding Scheme Project Grants

Notes Standard Project Grant