grant

Understanding skeletal development: A non-proteolytic mechanism of aggrecan resorption in the growth plate [ 2008 - 2011 ]

Also known as: Understanding skeletal development

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/508923]

Researchers: Prof Amanda Fosang (Principal investigator) ,  Dr Sharon Byers

Brief description Bone formation requires resorption of a cartilage template. We challenge the dogma that cartilage resorption is only by PROTEASES, and propose instead that GLYCOSIDASES might also be involved. Aims: Demonstrate that chondrocytes release glycosidases that are important for bone formation. Significance: New information for the design of reconstructive therapies for people with congenital and acquired limb deficiencies or inherited disorders such as arthritis and chondrodysplasias may be gained.

Funding Amount $AUD 563,044.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Identifiers
Viewed: [[ro.stat.viewed]]
ACN 633 798 857