Understanding the role of three-dimensional genome organisation in B cell lineage commitment and leukaemia. [ 2017 - ]

Research Grant

Researchers: Dr Timothy Johanson (Principal investigator)

Brief description Every one of your nuclei contain 2 metres of DNA. This DNA is 300,000 times longer than the nucleus itself. In order to fit into this space, while maintaining access to crucial genes, the DNA forms a fantastically ordered three-dimensional structure. This intricate organisation is crucial to health, with even minute changes driving diseases, such as cancer and heart disease. We propose using new technology to understand how this organisation changes during immune cell development and leukaemia.

Funding Amount $318,768.00

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF