Understanding the role of sugar metabolism in liver tumour growth [ 2016 - 2018 ]

Research Grant

Researchers: A/Pr Kyle Hoehn (Principal investigator) ,  A/Pr Nigel Turner

Brief description Primary liver cancer is a deadly disease with limited chemotherapeutic options. The investigators of this proposal have recently determined that sugar intake (but not fat or complex carbohydrate) is a dominant driver of liver tumour growth in mice. The current proposal will investigate the specific contributions of glucose versus fructose in tumour burden, and determine whether blocking the conversion of sugars to fat in the liver represents a therapeutic strategy to block tumour growth in mice.

Funding Amount $AUD 649,695.85

Funding Scheme Project Grants

Notes Standard Project Grant