grant

Understanding the role of SSB1 in embryonic development and genome maintenance [ 2012 - 2014 ]

Also known as: Understanding the physiological functions of SSB1

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1031327]

Researchers: Prof Kum Kum Khanna (Principal investigator) ,  A/Pr Kevin Spring

Brief description Normally DNA exists as a double helix where two strands are zipped together. When single-stranded (ss) DNA is exposed during various cellular processes it can be easily damaged and degraded by cellular enzymes, but is protected by ssDNA binding proteins (SSBs). We have identified two new SSBs (SSB1 and SSB2) that play a crucial role in DNA repair and will investigate the role and physiological function of these important proteins.

Funding Amount $AUD 620,716.41

Funding Scheme Project Grants

Notes Standard Project Grant

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