grant

Understanding the role of host Arih2 in defence against viral infection and disease pathogenesis [ 2013 - 2015 ]

Also known as: Arih2 and host anti-viral responses

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1045532]

Researchers: Prof Marc Pellegrini (Principal investigator)

Brief description A set of proteins, called E3 ligases, modulate many aspects of immunity. Arih 2 is a novel E3 ligase that limits immune cell activation to maintain the immune system in a quiescent state. The details of how Arih2 functions and its role in immunity to chronic overwhelming infection are the focus of this study. The insights gained from these studies have important implications for our understanding of how immune responses can be promoted during infection or halted in autoimmunity.

Funding Amount $AUD 537,737.15

Funding Scheme Project Grants

Notes Standard Project Grant

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