Understanding the role of circular RNAs in neuronal biology using RNA-targeting CRISPR/Cas9 [ 2016 - 2019 ]

Research Grant

Researchers: Dr Mitchell O'Connell (Principal investigator) ,  The Australian National University (Managed by)

Brief description The regulation of gene expression through a process known as RNA splicing has been shown to be at the heart of a number of processes required for brain development, memory and learning, and is often dysregulated in a number of neurological diseases. Circular RNAs (circRNAs) have been recently shown to be a relatively abundant class of spliced RNA that are specifically enriched in brain tissue. In this project, I aim to understand the roles of circRNAs in neuronal development.

Funding Amount $AUD 398,097.00

Funding Scheme Early Career Fellowships

Notes CJ Martin Biomedical ECF