grant

Understanding the regulation of cell polarity in development and cancer [ 2009 - 2012 ]

Also known as: Understanding cell orientation in development and cancer

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/566607]

Researchers: Prof Patrick Humbert (Principal investigator)

Brief description Cell polarity is the property of cells to be spatially oriented in a tissue or organ. We have now shown that the gene Scribble, a key regulator of cell orientation, may keep tumour development in check. In this proposal, we will examine how disruption of Scribble and associated molecules affects normal development and promotes cancer using a combination of tissue culture studies and a newly established mouse model. These studies may provide novel targets for therapeutic intervention in cancer.

Funding Amount $AUD 428,602.70

Funding Scheme Career Development Fellowships

Notes RD Wright Biomedical CDF

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Identifiers
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ACN 633 798 857