Understanding the parameters of innate immune activation that govern protection during influenza virus and secondary bacterial infection: development of a TLR2-based antimicrobial agent. [ 2014 - 2016 ]

Research Grant

Researchers: Prof David Jackson (Principal investigator) ,  Dr Amabel Tan ,  Prof Patrick Reading

Brief description Lower respiratory infections are the leading infectious cause of death worldwide. We have discovered a compound that reduces the impact and disease caused by viral and bacterial infections. This study will develop the prophylactic capabilities of this agent against transmission of influenza virus A and development of secondary bacterial disease. In addition, we will identify the mechanism of action for this compound, and its utility as a broad-spectrum intervention measure against viral and bacterial infections.

Funding Amount $AUD 462,420.15

Funding Scheme Project Grants

Notes Standard Project Grant