Understanding influenza-specific T cell immunity in the Indigenous population [ 2013 - 2016 ]

Research Grant

Researchers: Prof Katherine Kedzierska (Principal investigator) ,  A/Pr Steven Tong ,  Prof Adrian Miller

Brief description Hospitalisation and death rates from influenza are high in the Indigenous population. There is an urgent need for one-shot universal vaccine that protects against seasonal and pandemic strains. T cells recognising conserved viral regions can elicit such protection. As T cells are restricted by proteins called HLAs, variable between different ethnicities, we will define T cell regions and their HLA restrictions in the Indigenous population to propose strategies for universal T cell-based protective immunity and vaccine design against influenza.

Funding Amount $AUD 870,112.89

Funding Scheme Project Grants

Notes Standard Project Grant