Understanding the development of autoimmunity in response to citrullinated peptide antigen presentation to T cells in rheumatoid arthritis [ 2015 - 2019 ]

Research Grant

Researchers: Prof Ranjeny Thomas (Principal investigator) ,  Dr Hugh Reid

Brief description Rheumatoid arthritis (RA) is a systemic autoimmune disease predominantly affecting synovial joints, in 1% of adults worldwide. HLA-class II genes underlie the major genetic susceptibility to RA. The programme of work brings together 7 investigators from 3 countries to determine how autoimmunity develops to self antigens in individuals at genetic risk of RA and why resistance alleles are protective against RA, in Caucasian, Asian and North American Native populations. We will provide a molecular

Funding Amount $AUD 1,181,793.16

Funding Scheme Project Grants

Notes Standard Project Grant