Understanding how cytomegaloviruses establish systemic infection [ 2019 - 2022 ]

Research Grant

Researchers: A/Pr Philip Stevenson (Principal investigator) ,  Dr Helen Farrell

Brief description Human cytomegalovirus (HCMV) infects most Australians, causes birth defects and harms transplant patients. Vaccines against it have worked poorly. HCMV spreads throughout the body and is never cleared. To control infection we must identify its key checkpoints. Using mouse CMV, we find that host dendritic cells, which normally defend against infections, are taken over and spread virus to new sites. The viral gene responsible is a potential target for intervention. We will define how it works.

Funding Amount $AUD 677,498.00

Funding Scheme Project Grants

Notes Standard Project Grant