Understanding the causes of childhood congenital anomalies of the kidney and urinary tract [ 2012 - 2015 ]

Research Grant

Researchers: Prof John Bertram (Principal investigator) ,  A/Pr Paul James ,  Dr Georgina Caruana ,  Prof Yves Heloury

Brief description Congenital anomalies of the kidney and urinary tract (CAKUT) is a common cause of renal failure in children. The majority of patients with CAKUT do not know the underlying cause of their renal anomalies. In this proposal we will characterise the developmental events that are perturbed in three mouse models of CAKUT and identify the causal gene responsible in each mouse model. We will translate this information to the clinic by screening patients with CAKUT for mutations in these newly identified genes.

Funding Amount $AUD 609,748.74

Funding Scheme Project Grants

Notes Standard Project Grant