Uncovering novel roles of Escherichia coli flagella and LPS in uropathogenesis [ 2015 - 2018 ]

Research Grant

Researchers: Prof Glen Ulett (Principal investigator)

Brief description Urinary tract infections (UTI) are common infectious diseases in humans. Uropathogenic Escherichia coli (UPEC) cause most UTI. UPEC produce factors that promote their survival and influence disease such as flagella. We have identified anti-inflammatory responses as a key element of UTI and have shown that these responses contribute to control of UTI. In this project, we will investigate how the UPEC flagella component, FliC, contributes to anti-inflammatory responses and what this means for UTI.

Funding Amount $AUD 404,677.41

Funding Scheme Project Grants

Notes Standard Project Grant