grant

A tyrosine phosphatase that regulates adherens junctions, cell migration and the epithelial-mesenchymal transition [ 2004 - 2006 ]

Also known as: An enzyme that regulates cell-cell adhesion, migration and morphogenesis

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/278802]

Researchers: A/Pr Yeesim Khew-Goodall (Principal investigator)

Brief description Cell-cell adhesion which physically glues cells together to form tissues and organs, also controls processes in development, wound healing and cancer progression. I have identified a novel regulator of cell-cell adhesion that regulates cell migration and cell morphology. Since these events are crucial during metastasis (the spread of cancer) and during wound healing, understanding the function of this novel regulator may provide the basis for new approaches to developing therapeutics. Specifically, in this proposal I aim to further our understanding of the function of this novel regulator in normal physiology and to elucidate how its functions are regulated.

Funding Amount $AUD 496,500.00

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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