A tumour suppressor pathway that removes DNA-RNA hybrids [ 2018 - ]

Research Grant

Researchers: Dr Andrew Deans (Principal investigator) ,  A/Pr Jorg Heierhorst ,  Dr Wojciech Niedzwiedz

Brief description DNA:RNA hybrids are found normally in our chromosomes. But, the regions where DNA:RNA hybrids form are linked to chromosome changes that occur during breast and blood cancer development. We have uncovered why these chromosome changes occur, and have linked it to the important function of a cancer-associated gene called FANCM. Our study is exploring this important finding that has implications for both the cause and treatment of cancer.

Funding Amount $935,780.00

Funding Scheme Project Grants

Notes Standard Project Grant