grant

Tumour induced innate immune responses that control breast cancer metastases [ 2013 - 2015 ]

Also known as: Immune reponses that dictate metastatic spread in breast cancer

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1047747]

Researchers: Dr Belinda Parker (Principal investigator) ,  Prof Paul Hertzog

Brief description The mechanisms of breast cancer spread to bone are largely unknown. We have found that cross-talk between tumour cells and the immune system exists to induce anti-tumour immune responses. By decreasing the release of proteins known to activate immune responses (type I interferons), tumour cells can hide from such responses and spread to tissues such as bone. We aim to identify the immune responses activated by type I IFN and if restoration of these pathways can block breast cancer spread to bone.

Funding Amount $AUD 596,164.37

Funding Scheme Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857