Tuberous sclerosis and epilepsy: using resected tissue to understand pathogenesis and inform management [ 2017 - 2018 ]

Research Grant

Researchers: A/Pr Richard Leventer (Principal investigator) ,  A/Pr Paul Lockhart ,  Dr Anthony Harvey

Brief description Epilepsy is the commonest neurological disorder in childhood and seizures cannot be fully controlled by medications in 30%, often leading to developmental consequences. A major cause of drug-resistant epilepsy is a malformation of the brain’s surface. Surgery is sometimes used to remove these lesions to treat the epilepsy. We will study this tissue to understand its architecture, genetic basis and how it causes seizures. Our results will guide treatment including the best surgical approach.

Funding Amount $AUD 346,418.53

Funding Scheme Project Grants

Notes Standard Project Grant